In six research groups, our staff members explore disease-related issues in selected topics related to molecular biology and biochemistry. Close cooperation within the division in alignment with the center's main topics of interest ensures optimal research conditions.
The role of endothelial lipase (EL) in lipoprotein metabolism with an emphasis on EL-generated lipolytic products and structural and functional properties of EL-modified HDL
Role of lipid hydrolases in regulating lipid and energy metabolism in organelles, cells, organs and the entire organism
Relationships between lipid-mediated inflammatory signal networks, cerebrovascular dysfunction and the development of neurodegenerative disease
Regulatory mechanisms of mitochondrial activity and the role of mitochondria in cancer growth and processes of (cell) aging as the basis for the development of new active substances
Development and application of genetically encoded biosensors to investigate signaling and metabolic activity in cancer cells and cell degeneration
Molecular mechanisms of regulatory interaction of intrinsically disordered proteins and development of active substances in cancer and aging
Investigation of mitochondrial function in the aging process and in aging-associated diseases
Genetic epidemiology is a key step along the way to precision medicine as it investigates the connection between genomic variability and disease including potential modulatory effects of lifestyle and environmental factors.
