Lehrstuhl für Molekularbiologie und Biochemie

In eight research groups, our staff members explore disease-related issues in selected topics related to molecular biology and biochemistry. Close cooperation within the division in alignment with the center's main topics of interest ensures optimal research conditions.

Forschungsschwerpunkt Stoffwechsel

Metabolism

The role of endothelial lipase (EL) in lipoprotein metabolism with an emphasis on EL-generated lipolytic products and structural and functional properties of EL-modified HDL

Role of lipid hydrolases in regulating lipid and energy metabolism in organelles, cells, organs and the entire organism

Role of lipid-degrading enzymes (lipases) particularly in inflammatory and degenerative diseases of the central nervous system.

Forschungsschwerpunkt Signaling

Signaling

Regulatory mechanisms of mitochondrial activity and the role of mitochondria in cancer growth and processes of (cell) aging as the basis for the development of new active substances

Investigation of mitochondrial function in the aging process and in aging-associated diseases

Neural Signal Processing

Interactions between cancer cells and immune cells, with a particular focus on cytotoxic T cells

 

Forschungsschwerpunkt Präzisionsmedizin

Precision medicine

Genetic epidemiology is a key step along the way to precision medicine as it investigates the connection between genomic variability and disease including potential modulatory effects of lifestyle and environmental factors.